The PDRN Pink Collagen line includes toner pads, single-use serum vials, a spicule serum, a capsule cream, hydrogel masks and a lip mask. Medicube makes the face products for dryness, dullness, loss of firmness and uneven-looking tone, and the lip mask for lips that feel dry.

What PDRN is

Medicube describes salmon PDRN as DNA extracted from salmon, and says the extraction isolates small DNA fragments. Ingredient lists call it sodium DNA. Some packs, such as the toner pad jar, print “99%” next to PDRN. Where Medicube explains the figure, it says it refers to the raw material.

Medicube files the lip mask under PDRN rather than PDRN Pink Collagen. We group it with this line.

What each product is
  • PDRN Pink Collagen Toning Gel Toner Pad: 70 pads in a 120ml jar, with a pouch of PDRN essence that you pour over the pads before first use. After about 5 seconds they turn to gel. Wipe one over cleansed skin, or lay pads on dry or dull areas for 5 minutes, then wipe the skin with them.
  • PDRN Pink One Day Serum: 10 single-use vials of 1.5ml. Twist one open, spread the serum over clean skin and pat it in. If some is left, recap the vial and finish it within a day. Medicube says it can be used every day. Keep it away from the eyes.
  • PDRN Pink Collagen Exosome Shot 7500: a 30ml leave-on serum with spicules, which are fine, needle-shaped particles of hydrolysed sponge. Medicube says they shed with dead skin over several days.
  • PDRN Pink Collagen Capsule Cream: pink PDRN capsules in a clear gel, with 5% niacinamide on the jar. You mix the two as you apply. Our capsule cream guide gives Medicube’s ratios.
  • PDRN Pink Collagen Gel Mask: 4 pink hydrogel masks that turn clear as the essence absorbs, over about 3 to 4 hours or overnight.
  • PDRN Lip Sleeping Mask: a 10g overnight lip mask with salmon PDRN, collagen and shea butter.
The order to use them in

Putting the directions for each product together gives this order after cleansing:

  1. Toner pad: wipe one over the face.
  2. One Day Serum: one vial, patted in.
  3. Capsule Cream: after serum, morning and evening, on the face and neck.
  4. Gel Mask (at night): as the last step of your evening routine, taken off in the morning.

The gel mask can also go on during the day, after toner or serum, for 3 to 4 hours or until it turns clear.

The Lip Sleeping Mask goes on separately: a generous layer before bed, with what is left wiped off in the morning, or a thin layer during the day whenever your lips feel dry.

Evenings with the Exosome Shot 7500

The carton gives the Exosome Shot 7500 its own schedule: every 3 days, in the evening. It goes on first, straight after cleansing, over the face except the eyes and mouth. Press it in gently and leave it on. Medicube then suggests a moisturiser: its PDRN serum and cream, or any water-based one. The One Day Serum and the Capsule Cream above are both from this line. Medicube’s directions do not say whether to use the toner pads or the gel mask on the same evening.

What 7500 means

7500 is the name of a strength. Medicube makes the PDRN Pink Collagen Exosome Shot in two strengths. It recommends the 2000 for beginners, for daily use, and the 7500 for experienced users, on a 3-day cycle. Medicube’s One Day Exosome Shot 7500, a pore serum from its Exosome line, uses the same strength name.

Medicube’s strength chart labels the two versions “2,000 PPM” and “7,500 PPM” without saying which ingredient the figure measures. It is not the amount of PDRN in the serum: the ingredient list gives sodium DNA at 10 ppm.

Medicube says tingling, redness, itching or warmth can follow and may last for some time. It recommends a patch test for sensitive skin, and advises people new to spicule products not to use the shot with its AGE-R devices, such as the AGE-R Booster Pro Mini.

Ingredients to check
  • Salmon: every product in the line contains salmon-derived ingredients.
  • Milk: the Exosome Shot 7500 also contains milk exosome.
  • Retinol: it is in the ingredient lists of the Exosome Shot 7500 and the Toning Gel Toner Pad. The pads also contain LHA.
  • Fragrance and plant oils: the Gel Mask’s ingredient list includes fragrance. The toner pads contain rosemary leaf and chamomile flower oils.

Patch-test each product on a small area before you use it all over, and stop using it if irritation develops.

Shop the PDRN Pink Collagen line