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The One Day Exosome Shot 7500 is a leave-on ampoule with spicules of hydrolysed sponge, which Medicube describes as microscopic needle-shaped particles. Medicube recommends its 2000 strength for anyone new to spicule products and the 7500 for experienced users.

Key ingredients

• Hydrolysed sponge (spicules): the source of the tingling on application. Medicube says the spicules shed with dead skin over several days.
• Lacto exosome: listed as lactobacillus extracellular vesicles.
• AHA, BHA and PHA: citric acid, betaine salicylate and gluconolactone.
• Niacinamide (vitamin B3) and panthenol.

How to use

• Use in the evening after cleansing, once every 3 days, as the packaging directs.
• Apply over the whole face as your first step, keeping clear of the eyes and lips.
• Rub and press it in gently until absorbed. Leave it on.
• Finish with a moisturiser. Medicube suggests a water-based one.

Good to know

• 30ml pump bottle.
• Medicube says tingling, redness, itching or warmth can follow application and may last for a while. Change the amount or how often you use it to suit your skin.
• Patch-test first if your skin is sensitive, and stop using it if irritation develops.
• If spicule products are new to you, Medicube advises against pairing this with its AGE-R devices.
• No fragrance appears in the ingredient list.
• Medicube’s US store sells it as Zero Exosome Shot. The bottle comes in two designs, so yours may not match every photo.